Ellen Fung, PhD, RD

Adjunct Professor
Pediatrics

Dr. Fung has advanced training in nutrition and a long-standing curiosity on the impact of nutrition and physical activity on bone health in children and young adults with chronic disease. She has a passion for hemoglobin disorders including thalassemia and sickle cell disease and has been conducting much of her research within these populations for the last 2 decades. Dr. Fung is the Director of the Bone Density Clinic at UCSF Benioff Children’s Hospital Oakland and enjoys educating clinicians on the importance of achieving optimal bone health in childhood and adolescence. She is also the Director of the UCSF Summer Student Research Program which for the past 4 decades has been placing talented high school and college students from diverse backgrounds into local clinics and basic science labs to participate in active biomedical research. The overall goal of the program is to stimulate interest in health sciences for under-represented students, arming them with professional skills and confidence, thereby improving their likelihood of success in STEM careers.

Publications: 

Nutrition for Patients with Thalassemia and Pyruvate Kinase Deficiency: A guideline for clinicians

Nutrition for Patients with Thalassemia and Pyruvate Kinase Deficiency: A guideline for clinicians.

Fung, EB, Schryver T, Angastiniotis M.

Persistent bone and joint disease despite current treatments for mucopolysaccharidosis types I, II, and VI: data from a 10-year prospective study.

Journal of inherited metabolic disease

Miller BS, Fung EB, White KK, Lund TC, Harmatz P, Orchard PJ, Whitley CB, Polgreen LE

Interpretation of Bone Mineral Density Z-Scores by Dual-Energy X-Ray Absorptiometry in Transgender and Gender Diverse Youth Prior to Gender-Affirming Medical Therapy.

Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

Lee JY, Fan B, Montenegro G, Long RK, Sanda S, Capodanno G, Schafer AL, Burghardt AJ, Rosenthal SM, Fung EB

Kidney Stones in Transfusion Dependent Thalassemia: Prevalence and Risk Factors

Open Journal of Urology

Sayani FA, Lal A, Tasian GE, Al-Mukaddam M, Killilea DW, Wasserstein A, Fung EB.

Success of Distance Learning During 2020 COVID-19 Restrictions: A Report from Five STEM Training Programs for Underrepresented High School and Undergraduate Learners.

Journal of STEM outreach

Fung EB, Frey MR, Valmont ME, Caffey-Fleming DE, Fraser M, Williams J, Killilea DW, Bogenmann E, Livshits S, Boone DN

Zinc deficiency and its association with treatment-related toxicity in children with cancer.

Pediatric blood & cancer

Chung JH, Phalke N, Hastings C, Killilea DW, Feusner JH, Fung EB

Biomarkers for prediction of skeletal disease progression in mucopolysaccharidosis type I.

JIMD reports

Lund TC, Doherty TM, Eisengart JB, Freese RL, Rudser KD, Fung EB, Miller BS, White KK, Orchard PJ, Whitley CB, Polgreen LE

Zinc supplementation improves markers of glucose homeostasis in thalassaemia.

British journal of haematology

Fung EB, Ahmad T, Killilea DW, Hussain R, Lal A

Urinary cross-linked carboxyterminal telopeptide, a bone resorption marker, decreases after vaso-occlusive crises in adults with sickle cell disease.

Blood cells, molecules & diseases

Adesina OO, Jenkins IC, Wu QV, Fung EB, Narla RR, Lipkin EW, Mahajan K, Konkle BA, Kruse-Jarres R

Clinical trial of laronidase in Hurler syndrome after hematopoietic cell transplantation.

Pediatric research

Polgreen LE, Lund TC, Braunlin E, Tolar J, Miller BS, Fung E, Whitley CB, Eisengart JB, Northrop E, Rudser K, Miller WP, Orchard PJ

Precision of the Hologic DXA in the Assessment of Visceral Adipose Tissue.

Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

Goldberg EK, Fung EB

Effect of prenatal calcium supplementation on bone during pregnancy and 1 y postpartum.

The American journal of clinical nutrition

Cullers A, King JC, Van Loan M, Gildengorin G, Fung EB

Nutritional Deficiencies Are Common in Patients with Transfusion-Dependent Thalassemia and Associated with Iron Overload.

Journal of food and nutrition research (Newark, Del.)

Goldberg EK, Neogi S, Lal A, Higa A, Fung E

Vertebral Bone Density Measurements by DXA are Influenced by Hepatic Iron Overload in Patients with Hemoglobinopathies.

Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

Allard HM, Calvelli L, Weyhmiller MG, Gildengorin G, Fung EB

The Answer is Vitamin D! From Pediatrics to Geriatrics in Orthopaedics.

Instructional course lectures

Minkowitz B, Sawyer A, Fung EB, Dvorzhinskiy A, Lane JM

Dietary nonheme iron is equally bioavailable from ferritin or ferrous sulfate in thalassemia intermedia.

Pediatric hematology and oncology

Khurana M, Fung EB, Vichinsky EP, Theil EC

Effects of early vitamin D deficiency rickets on bone and dental health, growth and immunity.

Maternal & child nutrition

Zerofsky M, Ryder M, Bhatia S, Stephensen CB, King J, Fung EB

Guidelines for the Standard Monitoring of Patients With Thalassemia: Report of the Thalassemia Longitudinal Cohort.

Journal of pediatric hematology/oncology

Tubman VN, Fung EB, Vogiatzi M, Thompson AA, Rogers ZR, Neufeld EJ, Kwiatkowski JL, Thalassemia Clinical Research Network

Biomarkers of bone remodeling in children with mucopolysaccharidosis types I, II, and VI.

Journal of pediatric rehabilitation medicine

Stevenson DA, Rudser K, Kunin-Batson A, Fung EB, Viskochil D, Shapiro E, Orchard PJ, Whitley CB, Polgreen LE

Bone health in children with special health care needs.

Journal of pediatric rehabilitation medicine

Fung EB

The effect of low magnitude mechanical stimulation (LMMS) on bone density in patients with Rett syndrome: a pilot and feasibility study.

Journal of pediatric rehabilitation medicine

Afzal SY, Wender AR, Jones MD, Fung EB, Pico EL

Zinc supplementation improves bone density in patients with thalassemia: a double-blind, randomized, placebo-controlled trial.

The American journal of clinical nutrition

Fung EB, Kwiatkowski JL, Huang JN, Gildengorin G, King JC, Vichinsky EP

Low bone mineral content and challenges in interpretation of dual-energy X-ray absorptiometry in children with mucopolysaccharidosis types I, II, and VI.

Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

Polgreen LE, Thomas W, Fung E, Viskochil D, Stevenson DA, Steinberger J, Orchard P, Whitley CB, Ensrud KE

Increased leucocyte apoptosis in transfused �-thalassaemia patients.

British journal of haematology

Walter PB, Porter J, Evans P, Kwiatkowski JL, Neufeld EJ, Coates T, Giardina PJ, Grady RW, Vichinsky E, Olivieri N, Trachtenberg F, Alberti D, Fung E, Ames B, Higa A, Harmatz P, Thalassemia Clinical Research Network

The effect of whole body vibration therapy on bone density in patients with thalassemia: a pilot study.

American journal of hematology

Fung EB, Gariepy CA, Sawyer AJ, Higa A, Vichinsky EP

Feto-maternal vitamin D status and infant whole-body bone mineral content in the first weeks of life.

European journal of clinical nutrition

Dror DK, King JC, Durand DJ, Fung EB, Allen LH

Role of calcium during pregnancy: maternal and fetal needs.

Nutrition reviews

Hacker AN, Fung EB, King JC

Inadequate dietary intake in patients with thalassemia.

Journal of the Academy of Nutrition and Dietetics

Fung EB, Xu Y, Trachtenberg F, Odame I, Kwiatkowski JL, Neufeld EJ, Thompson AA, Boudreaux J, Quinn CT, Vichinsky EP, Thalassemia Clinical Research Network

Treatment of vitamin D deficiency in transfusion-dependent thalassemia.

American journal of hematology

Fung EB, Aguilar C, Micaily I, Haines D, Lal A

Characterization of low bone mass in young patients with thalassemia by DXA, pQCT and markers of bone turnover.

Bone

Fung EB, Vichinsky EP, Kwiatkowski JL, Huang J, Bachrach LK, Sawyer AJ, Zemel BS

Rapid remineralization of the distal radius after forearm fracture in children.

Journal of pediatric orthopedics

Fung EB, Humphrey ML, Gildengorin G, Goldstein N, Hoffinger SA

Renal dysfunction in patients with thalassaemia.

British journal of haematology

Quinn CT, Johnson VL, Kim HY, Trachtenberg F, Vogiatzi MG, Kwiatkowski JL, Neufeld EJ, Fung E, Oliveri N, Kirby M, Giardina PJ, Thalassemia Clinical Research Network

Nutritional deficiencies in patients with thalassemia.

Annals of the New York Academy of Sciences

Fung EB

Dual-energy X-ray absorptiometry with serum ferritin predicts liver iron concentration and changes in concentration better than ferritin alone.

Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

Shepherd JA, Fan B, Lu Y, Marquez L, Salama K, Hwang J, Fung EB

Relationship between chronic transfusion therapy and body composition in subjects with thalassemia.

The Journal of pediatrics

Fung EB, Xu Y, Kwiatkowski JL, Vogiatzi MG, Neufeld E, Olivieri N, Vichinsky EP, Giardina PJ, Thalassemia Clinical Research Network

Randomized, controlled trial to examine the impact of providing yogurt to women enrolled in WIC.

Journal of nutrition education and behavior

Fung EB, Ritchie LD, Walker BH, Gildengorin G, Crawford PB

Bone density assessment in patients with mucopolysaccharidosis: A preliminary report from patients with MPS II and VI.

Journal of pediatric rehabilitation medicine

Fung EB, Johnson JA, Madden J, Kim T, Harmatz P

Hemoglobin H-constant spring in North America: an alpha thalassemia with frequent complications.

American journal of hematology

Singer ST, Kim HY, Olivieri NF, Kwiatkowski JL, Coates TD, Carson S, Neufeld E, Cunningham MJ, Giardina PJ, Mueller BU, Quinn CT, Fung E, Vichinsky E, Thalassemia Clinical Research Network

Differences in the prevalence of growth, endocrine and vitamin D abnormalities among the various thalassaemia syndromes in North America.

British journal of haematology

Vogiatzi MG, Macklin EA, Trachtenberg FL, Fung EB, Cheung AM, Vichinsky E, Olivieri N, Kirby M, Kwiatkowski JL, Cunningham M, Holm IA, Fleisher M, Grady RW, Peterson CM, Giardina PJ, Thalassemia Clinical Research Network

Bone disease in thalassemia: a frequent and still unresolved problem.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Vogiatzi MG, Macklin EA, Fung EB, Cheung AM, Vichinsky E, Olivieri N, Kirby M, Kwiatkowski JL, Cunningham M, Holm IA, Lane J, Schneider R, Fleisher M, Grady RW, Peterson CC, Giardina PJ, Thalassemia Clinical Research Network

The work and home activities questionnaire: energy expenditure estimates and association with percent body fat.

Journal of physical activity & health

Block G, Jensen CD, Block TJ, Norris J, Dalvi TB, Fung EB

Vitamin C treatment reduces elevated C-reactive protein.

Free radical biology & medicine

Block G, Jensen CD, Dalvi TB, Norkus EP, Hudes M, Crawford PB, Holland N, Fung EB, Schumacher L, Harmatz P

Disparity in the management of iron overload between patients with sickle cell disease and thalassemia who received transfusions.

Transfusion

Fung EB, Harmatz PR, Milet M, Balasa V, Ballas SK, Casella JF, Hilliard L, Kutlar A, McClain KL, Olivieri NF, Porter JB, Vichinsky EP, Multi-Center Iron Overload Research Group

The effect of vitamins C and E on biomarkers of oxidative stress depends on baseline level.

Free radical biology & medicine

Block G, Jensen CD, Morrow JD, Holland N, Norkus EP, Milne GL, Hudes M, Dalvi TB, Crawford PB, Fung EB, Schumacher L, Harmatz P

Fracture prevalence and relationship to endocrinopathy in iron overloaded patients with sickle cell disease and thalassemia.

Bone

Fung EB, Harmatz PR, Milet M, Coates TD, Thompson AA, Ranalli M, Mignaca R, Scher C, Giardina P, Robertson S, Neumayr L, Vichinsky EP, Multi-Center Iron Overload Study Group

Markers of bone turnover are associated with growth and development in young subjects with sickle cell anemia.

Pediatric blood & cancer

Fung EB, Kawchak DA, Zemel BS, Rovner AJ, Ohene-Frempong K, Stallings VA

Morbidity and mortality in chronically transfused subjects with thalassemia and sickle cell disease: A report from the multi-center study of iron overload.

American journal of hematology

Fung EB, Harmatz P, Milet M, Ballas SK, De Castro L, Hagar W, Owen W, Olivieri N, Smith-Whitley K, Darbari D, Wang W, Vichinsky E, Multi-Center Study of Iron Overload Research Group

A randomised comparison of deferasirox versus deferoxamine for the treatment of transfusional iron overload in sickle cell disease.

British journal of haematology

Vichinsky E, Onyekwere O, Porter J, Swerdlow P, Eckman J, Lane P, Files B, Hassell K, Kelly P, Wilson F, Bernaudin F, Forni GL, Okpala I, Ressayre-Djaffer C, Alberti D, Holland J, Marks P, Fung E, Fischer R, Mueller BU, Coates T, Deferasirox in Sickle Cell Investigators

Bone mineral density in children with sickle cell anemia.

Pediatric blood & cancer

Lal A, Fung EB, Pakbaz Z, Hackney-Stephens E, Vichinsky EP

Increased prevalence of iron-overload associated endocrinopathy in thalassaemia versus sickle-cell disease.

British journal of haematology

Fung EB, Harmatz PR, Lee PD, Milet M, Bellevue R, Jeng MR, Kalinyak KA, Hudes M, Bhatia S, Vichinsky EP, Multi-Centre Study of Iron Overload Research Group

Oxidative stress and inflammation in iron-overloaded patients with beta-thalassaemia or sickle cell disease.

British journal of haematology

Walter PB, Fung EB, Killilea DW, Jiang Q, Hudes M, Madden J, Porter J, Evans P, Vichinsky E, Harmatz P

Growth and health in children with moderate-to-severe cerebral palsy.

Pediatrics

Stevenson RD, Conaway M, Chumlea WC, Rosenbaum P, Fung EB, Henderson RC, Worley G, Liptak G, O'Donnell M, Samson-Fang L, Stallings VA, North American Growth in Cerebral Palsy Study

Prevalence of fractures among the Thalassemia syndromes in North America.

Bone

Vogiatzi MG, Macklin EA, Fung EB, Vichinsky E, Olivieri N, Kwiatkowski J, Cohen A, Neufeld E, Giardina PJ

Bone scintigraphy in common tumors with osteolytic components.

Clinical nuclear medicine

Wang K, Allen L, Fung E, Chan CC, Chan JC, Griffith JF

Comparison of organ dysfunction in transfused patients with SCD or beta thalassemia.

American journal of hematology

Vichinsky E, Butensky E, Fung E, Hudes M, Theil E, Ferrell L, Williams R, Louie L, Lee PD, Harmatz P

A simple model to assess and improve adherence to iron chelation therapy with deferoxamine in patients with thalassemia.

Annals of the New York Academy of Sciences

Pakbaz Z, Fischer R, Treadwell M, Yamashita R, Fung EB, Calvelli L, Quirolo K, Foote D, Harmatz P, Vichinsky EP

Interaction of artificial metallic objects with biosusceptometric measurements.

Neurology & clinical neurophysiology : NCN

Engelhardt R, Fung EB, Kelly P, Biehl TR, Pakbaz Z, Nielsen P, Harmatz P, Fischer R

The new SQUID biosusceptometer at Oakland: first year of experience.

Neurology & clinical neurophysiology : NCN

Fung EB, Fischer R, Pakbaz Z, Fagaly RL, Vichinsky E, Starr TN, Ewing T, Paulson DN, Hassenzahl WV, Harmatz P

Plasma zinc is an insensitive predictor of zinc status: use of plasma zinc in children with sickle cell disease.

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition

Fung EB, Kawchak DA, Zemel BS, Ohene-Frempong K, Stallings VA

Relationship of nutritional status to health and societal participation in children with cerebral palsy.

The Journal of pediatrics

Samson-Fang L, Fung E, Stallings VA, Conaway M, Worley G, Rosenbaum P, Calvert R, O'donnell M, Henderson RC, Chumlea WC, Liptak GS, Stevenson RD

Secondary sexual characteristics in children with cerebral palsy and moderate to severe motor impairment: a cross-sectional survey.

Pediatrics

Worley G, Houlihan CM, Herman-Giddens ME, O'Donnell ME, Conaway M, Stallings VA, Chumlea WC, Henderson RC, Fung EB, Rosenbaum PL, Samson-Fang L, Liptak GS, Calvert RE, Stevenson RD

Bone density and metabolism in children and adolescents with moderate to severe cerebral palsy.

Pediatrics

Henderson RC, Lark RK, Gurka MJ, Worley G, Fung EB, Conaway M, Stallings VA, Stevenson RD

Feeding dysfunction is associated with poor growth and health status in children with cerebral palsy.

Journal of the American Dietetic Association

Fung EB, Samson-Fang L, Stallings VA, Conaway M, Liptak G, Henderson RC, Worley G, O'Donnell M, Calvert R, Rosenbaum P, Chumlea W, Stevenson RD

Effect of zinc supplementation on growth and body composition in children with sickle cell disease.

The American journal of clinical nutrition

Zemel BS, Kawchak DA, Fung EB, Ohene-Frempong K, Stallings VA

Pediatric reference data for dual X-ray absorptiometric measures of normal bone density in the distal femur.

AJR. American journal of roentgenology

Henderson RC, Lark RK, Newman JE, Kecskemethy H, Fung EB, Renner JB, Harcke HT

Effect of hydroxyurea therapy on resting energy expenditure in children with sickle cell disease.

Journal of pediatric hematology/oncology

Fung EB, Barden EM, Kawchak DA, Zemel BS, Ohene-Frempong K, Stallings VA

Health status of children with moderate to severe cerebral palsy.

Developmental medicine and child neurology

Liptak GS, O'Donnell M, Conaway M, Chumlea WC, Wolrey G, Henderson RC, Fung E, Stallings VA, Samson-Fang L, Calvert R, Rosenbaum P, Stevenson RD

Energy expenditure and intake in children with sickle cell disease during acute illness.

Clinical nutrition (Edinburgh, Scotland)

Fung EB, Malinauskas BM, Kawchak DA, Koh BY, Zemel BS, Gropper SS, Ohene-Frempong K, Stallings VA

Red blood cell folate and serum vitamin B12 status in children with sickle cell disease.

Journal of pediatric hematology/oncology

Kennedy TS, Fung EB, Kawchak DA, Zemel BS, Ohene-Frempong K, Stallings VA

Dual X-ray absorptiometry assessment of body composition in children with altered body posture.

Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

Henderson RC, Lark RK, Renner JB, Fung EB, Stallings VA, Conaway M, Stevenson RD

A six-month study of growth and energy expenditure in children with cystic fibrosis taking a pulmonary inhalation medication (rhDNase).

Journal of the American College of Nutrition

Fung EB, Barden EM, Wasserman D, Zemel BS, Heinrich BT, Scanlin TF, Stallings VA

A longitudinal study of calcium homeostasis during human pregnancy and lactation and after resumption of menses.

The American journal of clinical nutrition

Ritchie LD, Fung EB, Halloran BP, Turnlund JR, Van Loan MD, Cann CE, King JC

Zinc absorption in women during pregnancy and lactation: a longitudinal study.

The American journal of clinical nutrition

Fung EB, Ritchie LD, Woodhouse LR, Roehl R, King JC

Urinary lactose excretion is not an index of lactation performance.

Journal of the American Dietetic Association

Yoon JS, Fung EB, Ritchie LD, Woodhouse LR, King JC

Role: