04: Blood Transfusions
4.1 | Assessing the need for routine transfusions |
4.2 | Baseline laboratory tests prior to regular transfusions |
4.3 | Transfusion administration and monitoring |
4.3.1 | Transfusion facility |
4.3.2 | Type of blood product |
4.3.3 | Target hemoglobin and frequency of transfusions |
4.4 | Adverse reactions to transfusions |
4.5 | Splenectomy |
4.6 | Thromboembolic Disease |
05: Iron Overload and Chelation Therapy
5.1 | Initiation of chelation |
5.2 | Treatment with iron chelators |
5.2.1 | Treatment with deferoxamine (Desferal) |
5.2.2 | Treatment with deferasirox (Exjade) |
5.2.3 | Treatment with deferiprone (L1/Ferriprox) |
5.3 | Patients with significant iron overload |
5.3.1 | High-dose, continuous deferoxamine |
5.3.2 | Combination therapy: deferoxamine and deferasirox |
5.3.3 | Combination therapy: deferoxamine and deferiprone |